Paru le 08/02/2016 | Broché 299 pages
Professionnels
Oxidative stress and women's health
Under the supervision of Yves Ménézo
The aim of this book is to demonstrate the impact of oxidative stress on woman health with a special focus on reproduction and genome transmission. The determination of the female specific markers of oxidative stress will be approached
The book will cover : The role of ROS in gamete damaging, early embryonic development perturbation, polycystic ovarian syndrome and endometriosis generation, contraception, menopause and pregnancy pathological aspects.
The metabolic and biochemical aspects, especially concerning lipid and DNA, leading to these pathologies including carcinogenesis will be explained, when possible. Some ROS linked perturbation in animals will be also presented In fine, the authors will shortly develop their own feelings on the ways to prevent and even cure, when possible, these pathological aspects.
Yves Ménézo got his Ph D thesis in 1971 from the University of Lyon (France) and then his Dr of Sciences in 1979. His work is devoted to the metabolism of the preimplantation embryo and the metabolic exchanges
with the female genital tract. He has been first à researcher at INRA the French Public Institute for Agricultural Research. He designed in 1976 the first synthetic culture medium for reproductive biotechnologies in farm animals. He has been nominated as associated Professor in the department of animal sciences at the LSU, Louisiana State University in Baton Rouge. Then he left INRA in 1990 to follow Dr Charles Mérieux at the Mérieux Foundation as head of the ART Unity.
He left in 2007 and is now an independent scientific adviser.
His research is currently focused on epigenetic problems in reproduction and their possible impacts on future generations. Pr Menezo has published more than 250 scientific papers and book chapters and developed several patents
and « know how ».